Bioinformatics · Machine Learning · Cancer Genomics

Computational methods for genomics, cancer evolution, and biological discovery.

The DeepBioMed Lab develops computational approaches for analyzing large-scale biological data, with a focus on structural variation detection, cancer heterogeneity, and single-cell genomics. Our work draws from machine learning, statistical inference, and optimization to better understand complex biological systems.

Structural variation detection
Cancer heterogeneity
Single-cell bioinformatics
Group photo of the DeepBioMed Lab
The Team
Overview

About the lab

We are interested in developing scalable computational tools that turn complex genomic and sequencing data into biological insight. The lab’s research spans algorithm development, machine learning, and integrative analysis for studying variation, tumor evolution, and heterogeneity in cancer.

Research

Current research directions

Our research combines computational rigor with biological relevance, emphasizing methods that can address real questions in genomics and cancer biology.

Theme 01

Structural Variation Detection

Developing computational methods to detect and characterize large-scale genomic variation across diverse sequencing technologies.

Theme 02

Cancer Heterogeneity and Evolution

Building tools to study tumor subclones, infer evolutionary history, and understand how cancer changes over time.

Theme 03

Machine Learning for Genomics

Applying machine learning and statistical inference to large-scale biological and single-cell data for more accurate and interpretable analysis.

Publications

Featured work

Selected publications are loaded automatically from the publications JSON file.

People

Lab members

The lab is led by Prof. Xian Mallory and currently includes four PhD students.

Portrait of Prof. Xian Mallory

Xian Mallory

Principal Investigator

Prof. Mallory develops computational techniques for analyzing biological data, with emphasis on cancer, structural variation, machine learning, and sequencing-based inference.

Current PhD Students

We currently have four PhD students in the lab:

  • Pankaj Bhattarai
  • Noor Mohammad Talukder
  • Utkarsh Goyal
  • Tanha Kabir Koly
Opportunities

Join the lab

We welcome students interested in bioinformatics, computational biology, cancer genomics, machine learning, and large-scale sequencing data analysis.

Prospective students

If you are interested in joining the lab, please reach out with your background, research interests, and CV. Strong preparation in programming, algorithms, statistics, and mathematics is especially valuable.

News

Latest updates

This section to have news and updates.

Apr, 2026

New paper!

scLongTree's revision has been updated on bioRxiv